Fig. 5

P-gp and BCRP gene expression in CIPp and CIPm treated with DOX EC50(20h). Gene expression is calculated with the formula of 2 –ΔΔCt and shows the fold of change of treated cells vs their relative controls. The bars represent the minimum and maximum expression range of the genes. Asterisk indicates statistically significant differences (p < 0.05) calculated with the Student’s t test (comparing treated vs ctr at the same time points)